top of page
07022025_nos_mcherryRNAi_ad_tes_vasa488_boule546_FasIII633_10x_1_merge.tif

Van Doren Lab
Publications

2021-2025

  • Pozmanter C., Benner L., Kelly SE., Curnutte H., Emilfork L., Van Doren M. (2025). Tudor domain containing protein 5-like identifies a novel germline body and regulates maternal RNAs during oogenesis in Drosophila. Genetics. DOI: 10.1093/genetics/iyaf024

  • Goyal R., Baxter E., Van Doren M. (2024). Sisterless A is required for activation of Sex lethal in the Drosophila germline. eLife.  DOI: 10.7554/eLife.100491.1

  • Grmai L., Jimenez E., Baxter E., Van Doren M. (2023). Steroid signaling controls sex-specific development in an invertebrate. bioRxiv. DOI: 573099

  • Pozmanter C., Van Doren M. (2023). Germline sex determination: How males and females tame transposons in their own ways. Current Biology, 33, R442-R444. DOI: 04001

  • Bhaskar P., Southard S., Baxter K., Van Doren M. (2022). Germline Sex Determination regulates sex-specific signaling between germline stem cells and their niche. Cell Reports, 39, 110620. PMID: 35385723

  • Grmai L., Pozmanter C., Van Doren M. (2022). The Regulation of Germline Sex Determination in Drosophila by Sex lethal. Sexual Development, 1-6. PMID: 35259743

  • Zhou H., Whitworth C., Pozmanter C., Neville M.C., Van Doren M. (2021). Doublesex regulates fruitless expression to promote sexual dimorphism of the gonad stem cell niche. PLoS Genetics, 17, e1009468. PMID: 33788836

2016-2020

​

  • Primus S., Pozmanter C., Baxter K., Van Doren M. (2019). Tudor-domain containing protein 5-like promotes male sexual identity in the Drosophila germline and is repressed in females by Sex lethal. PLoS Genetics. 15, e1007617. PMID: 31329582

  • Camara N., Whitworth C., Dove A., Van Doren M. (2019). Doublesex controls specification and maintenance of the gonad stem cell niches in Drosophila. Development. 146, dev170001. PMID: 31043421

  • Yang SY., Chang YC., Wan YH., Whitworth C., Baxter EM., Primus S., Pi H., Van Doren M. (2017). Control of a Novel Spermatocyte-Promoting Factor by the Male Germline Sex Determination Factor PHF7 of Drosophila melanogaster. Genetics. 206, 1939-1949. PMID: 28588035

2010-2015

​​

  • Clough E., Jimenez E., Kim Y.A., Whitworth C., Neville M.C., Hempel L.U., Pavlou H.J., Chen Z.X., Sturgill D., Dale R.K., Smith H.E., Przytycka T.M., Goodwin S.F., Van Doren M., Oliver B. (2014). Sex- and tissue-specific functions of Drosophila doublesex transcription factor target genes. Developmental Cell. 31, 761-773. PMID: 25535918

  • Arbeitman M.N., Kopp A., Siegal M.L., Van Doren, M. (2014). The genetics of sex: exploring differences. Genetics. 197, 527-529. PMID: 24939993

  • Whitworth C., Jimenez E., Van Doren M. (2012). Development of sexual dimorphism in the Drosophila testis. Spermatogenesis. 2, 129-136. PMID: 23087832

  • Yang S.Y., Baxter E.M. Van Doren M. (2012). Phf7 controls male sex determination in the Drosophila germline. Developmental Cell. 22, 1041-1051. PMID: 22595675

  • Jemc J.C., Milutinovich A.B., Weyers J.J., Takeda Y. and Van Doren M. (2012). raw Functions through JNK signaling and cadherin-based adhesion to regulate Drosophila gonad morphogenesis. Developmental Biology. 367, 114-125. PMID: 22575490

  • Van Doren, M. (2011). Development: Determining Sexual Identity (perspective). Science. 333, 829-830. PMID: 21836003

  • Casper A.L. and Van Doren M. (2011). no child left behind encodes a novel chromatin factor required for germline stem cell maintenance in males but not females. Development. 138, 3357-3366. PMID: 21752937

  • Weyers, J.J., Milutinovich, A.B., Takeda, Y., Jemc, J.C. and Van Doren, M. (2011). A genetic screen for mutations affecting gonad formation in Drosophila reveals a role for the slit/robo pathway. Developmental Biology. 353, 217-228. PMID: 21377458

  • Van Doren, M. (2010). The cell biology of the germ cell life cycle. Current Opinion in Cell Biology. 22, 707-708. PMID: 21093242

  • Murray, S., Yang, S. and Van Doren, M. (2010). Germline Sex Determination: a collaboration between soma and germline. Current Opinion in Cell Biology. 22, 722-729. PMID: 21030233

  • Arbeitman, M.N., Kopp, A., Siegal, M.L. and Van Doren, M. (2010). Everything you always wanted to know about sex…in flies. Sexual Development. 4, 315-320. PMID: 20926851​

Before 2010

​​​

  • Casper A.L. and Van Doren M. (2009). The establishment of sexual identity in the Drosophila germline. Development. 136, 3821-3830. PMID: 19855024

  • Sheng X.R., Posenau T., Gumulak-Smith J.J., Matunis E., Van Doren M., Wawersik M. (2009). Jak-STAT regulation of male germline stem cell establishment during Drosophila embryogenesis. Developmental Biology. 334, 335-344. PMID: 19643104

  • Nanda S., DeFalco T.J., Loh S.H., Phochanukul N., Camara N., Van Doren M., Russell S. (2009). Sox100B, a Drosophila group E Sox-domain gene, is required for somatic testis differentiation. Sexual Development. 3, 26-37. PMID: 19339815

  • Camara N., Whitworth C., Van Doren, M. (2008). The creation of sexual dimorphism in the Drosophila soma. Current Topics in Developmental Biology. 83, 65-107. PMID: 19118664

  • Van Doren M. (2008). Sex determination and sexual development. Preface. Current Topics in Developmental Biology. 83, xi-xii. PMID: 19118661

  • DeFalco T.J., Camara N., Le Bras S., Van Doren, M. (2008). Non-autonomous sex determination controls sexually dimorphic development of the Drosophila gonad. Developmental Cell. 14, 285-286. PMID: 18267095

  • Van Doren M. (2007). Much HUBbub about stem-cell niches. Nature Cell Biology. 19, 1344-1245. PMID: 18059357

  • Casper A., Van Doren M. (2006). The control of sexual identity in the Drosophila germline. Development. 133, 2783-2791. PMID: 16835435

  • LeBras S., Van Doren M. (2006). Development of the male germline stem cell niche in Drosophila. Developmental Biology. 294, 92-103. PMID: 16566915

  • Mathews W.R., Ong D., Milutinovich A.J., Van Doren M. (2006). Zinc transport activity of Fear of Intimacy is essential for proper gonad morphogenesis and DE-cadherin expression. Development. 133, 1143-1153. PMID: 16481356

  • Wawersik M., Milutinovich A.B., Matunis E., Williams B., Van Doren M. (2005). Somatic control of germline sexual development is mediated by the JAK/STAT pathway. Nature. 436, 563-567. PMID: 16049490

  • Wawersik M., Van Doren M. (2005). nanos is required for formation of the spectrosome, a germ cell-specific organelle. Developmental Dynamics. 234, 22-27. PMID: 16028275

  • Mathews W.R., Wang F., Eide D.J., Van Doren M. (2005). Drosophila fear of intimacy encodes a Zrt/IRT-like protein (ZIP) family zinc transporter functionally related to mammalian ZIP proteins. J. Biological Chemistry. 280, 787-795. PMID: 15509557

  • DeFalco T.J., Le Bras S., Van Doren M. (2004). Abdominal-B is essential for proper sexually dimorphic development of the Drosophila gonad. Mechanisms of Development. 121, 1323-1333. PMID: 15454263

  • DeFalco T., Verney G., Jenkins A., McCaffery J.M., Russell S., Van Doren M. (2003). Sex-specific apoptosis regulates sexual dimorphism in the Drosophila embryonic gonad. Developmental Cell. 5, 205-16. PMID: 12919673

  • Jenkins A., McCaffery M., Van Doren M. (2003). Drosophila E-cadherin is essential for proper germ cell-soma interaction during gonad morphogenesis. Development. 130, 4417-26. PMID: 12900457

  • Van Doren M., Mathews W., Samuels M., Broihier H.T., Moore L.A., Lehmann, R. (2003). Fear of Intimacy encodes a conserved cell surface protein required for morphogenesis of the Drosophila gonad. Development. 130, 2355-2364. PMID: 12702650

  • (These papers have been featured in a Current Biology Dispatch article by D. Godt and U. Tepass. Current Biology. 13, R683-685)

  • Van Doren M., Moore L.A., Broihier H.T., Lehmann R. (1998). HMG-CoA reductase guides migrating primordial germ cells. Nature. 396, 466-469. PMID: 9853754

  • Van Doren M., Williamson A.L., Lehmann R. (1998). Regulation of zygotic gene expression in Drosophila primordial germ cells. Current Biology. 8, 243-246. PMID: 9501989

  • Van Doren M., Moore L.A., Broihier H.T., Lunsford L., Lehmann R. (1998). Identification of genes controlling germ cell migration and embryonic gonad formation in Drosophila. Development. 125, 667-678. PMID: 9435287

bottom of page